MOTS-c, also known as Mitochondrial-Derived Peptide MOTS-c, is a novel peptide that has been shown to have significant implications in the field of biochemistry and medical research. It is a 16-amino-acid peptide encoded in the mitochondria, specifically within the 12S rRNA gene.
Research on MOTS-c has illuminated its role in regulating metabolic homeostasis. This peptide has been found to enhance glucose uptake and fatty acid oxidation in skeletal muscle, thereby improving insulin sensitivity and overall metabolic health. It can potentially be used to combat metabolic disorders such as diabetes and obesity.
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[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4350682/
[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5663826/
[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC6500645/
[4] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC6046248/
[5] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC6567243/
[6] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC7343442/
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